ParkinsonCanadaV1, Main, Exploration, bibRecord, 000946

Reluctance to start medication for Parkinson's disease: a mutual misunderstanding by patients and physicians.

Identifieur interne : 000946 ( Main/Exploration ); précédent : 000945; suivant : 000947

Reluctance to start medication for Parkinson's disease: a mutual misunderstanding by patients and physicians.

Auteurs : Tiago A. Mestre [Canada] ; Tiago Teodoro [Portugal] ; William Reginold [Canada] ; Julia Graf [Allemagne] ; Maike Kasten [Allemagne] ; Joanna Sale [Canada] ; Mateusz Zurowski [Canada] ; Janis Miyasaki [Canada] ; Joaquim J. Ferreira [Portugal] ; Connie Marras [Canada]

Source :

Parkinsonism & related disorders [ 1873-5126 ] ; 2014.

RBID : pubmed:24661467

English descriptors

KwdEn :
- Aged, Antiparkinson Agents (therapeutic use), Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Parkinson Disease (drug therapy), Parkinson Disease (psychology), Physician-Patient Relations, Physicians (psychology), Practice Patterns, Physicians', Surveys and Questionnaires.
MESH :
- chemical , therapeutic use : Antiparkinson Agents.
- drug therapy : Parkinson Disease.
- psychology : Parkinson Disease, Physicians.
- Aged, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Physician-Patient Relations, Practice Patterns, Physicians', Surveys and Questionnaires.

Abstract

Reluctance to start medication has never been investigated before in PD. We studied reluctance to start medication for PD motor symptoms, namely its prevalence, underlying reasons, drug-specificity, and associated delay in the start of PD medication. A cross-sectional observational international study was conducted. Patients with a clinical diagnosis of PD advised to start antiparkinsonian medication in the previous 5 years were invited to complete a questionnaire in three centers located in North America and Europe. An electronic online survey was sent to physicians through the mailing list of the Movement Disorder Society. 469 participants (201 PD patients, 268 physicians). 40.2% (n = 82) of the patients reported reluctance to start medication, but 88.6% (n = 234/264) of the physicians estimated that ≤20% of their patients with PD had been reluctant to start medication. The most common reasons reported by patients were the fear of side effects (n = 35, 55.6%), followed by non-acceptance of diagnosis (n = 23, 36.5%); fear of a temporally limited benefit was more commonly selected by physicians (n = 92/267, 34.5%). Patients indicated reluctance to start DAs more frequently compared with L-DOPA (OR: 2.22, 95% CI: 1.30, 9.03; p = 0.013) while physicians perceived L-DOPA to be associated with more reluctance (OR: 4.7, 95% CI: 3.41; 6.59; p < 0.0001). Patients with PD and physicians have a different perspective on the issue of reluctance to start medication. There is a need to bring physicians and patients with PD closer to a shared vision of the problem reluctance to start medication.

DOI: 10.1016/j.parkreldis.2014.03.001
PubMed: 24661467

Affiliations:

Allemagne, Canada, Portugal

Le document en format XML

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<front><div type="abstract" xml:lang="en">Reluctance to start medication has never been investigated before in PD. We studied reluctance to start medication for PD motor symptoms, namely its prevalence, underlying reasons, drug-specificity, and associated delay in the start of PD medication. A cross-sectional observational international study was conducted. Patients with a clinical diagnosis of PD advised to start antiparkinsonian medication in the previous 5 years were invited to complete a questionnaire in three centers located in North America and Europe. An electronic online survey was sent to physicians through the mailing list of the Movement Disorder Society. 469 participants (201 PD patients, 268 physicians). 40.2% (n = 82) of the patients reported reluctance to start medication, but 88.6% (n = 234/264) of the physicians estimated that ≤20% of their patients with PD had been reluctant to start medication. The most common reasons reported by patients were the fear of side effects (n = 35, 55.6%), followed by non-acceptance of diagnosis (n = 23, 36.5%); fear of a temporally limited benefit was more commonly selected by physicians (n = 92/267, 34.5%). Patients indicated reluctance to start DAs more frequently compared with L-DOPA (OR: 2.22, 95% CI: 1.30, 9.03; p = 0.013) while physicians perceived L-DOPA to be associated with more reluctance (OR: 4.7, 95% CI: 3.41; 6.59; p < 0.0001). Patients with PD and physicians have a different perspective on the issue of reluctance to start medication. There is a need to bring physicians and patients with PD closer to a shared vision of the problem reluctance to start medication.</div>
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La maladie de Parkinson au Canada (serveur d'exploration)

Reluctance to start medication for Parkinson's disease: a mutual misunderstanding by patients and physicians.

Reluctance to start medication for Parkinson's disease: a mutual misunderstanding by patients and physicians.

Source :

English descriptors

Abstract

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	La maladie de Parkinson au Canada (serveur d'exploration)
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